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SLU-PP-915Research reference

SLU-PP-915 / Study library

Research, with context.

Filter by study model, then open the original record to examine methods and findings.

3 studies shown

STUDY 01 · 2023
Chemical series, receptor assays, muscle cells, and mice

Development and pharmacological evaluation of a new chemical series of potent pan-ERR agonists, identification of SLU-PP-915

The study identified SLU-PP-915 and connected its receptor activity to changes in ERR target-gene expression. It also examined metabolic stability during chemical optimization.

Reading limit: This is early pharmacology and compound development. It does not establish clinical effectiveness, a human exposure target, or long-term safety.

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STUDY 02 · 2026
Mice; exercise and gene-expression experiments

An orally active estrogen receptor-related receptor agonist, SLU-PP-915, enhances aerobic exercise capacity

Investigators reported increased treadmill performance with oral SLU-PP-915 and compared responses with SLU-PP-332 after accounting for systemic exposure. They also examined gene-expression changes alongside exercise training.

Reading limit: Oral activity in mice is not a demonstration of human oral effectiveness or equivalence with a particular capsule product.

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STUDY 03 · 2024
Neonatal rat ventricular myocytes and mouse muscle-cell line

The Estrogen Receptor-Related Orphan Receptors Regulate Autophagy through TFEB

The researchers identified TFEB as a direct ERR-regulated gene and found increased TFEB-related expression after ERR activation. SLU-PP-915 was used to investigate this connection in cell preparations.

Reading limit: Cellular pathway measurements do not establish clinical rejuvenation, disease prevention, or a lifespan effect.

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How this guide was prepared

We reviewed the linked primary publications and source records for the claims summarized here. This is a focused educational selection, not a systematic review or a clinical recommendation. Scientific findings are kept separate from supplier catalog descriptions.

The selected evidence comes from laboratory and animal studies. It does not establish human efficacy, an appropriate human-use protocol, or the safety and performance of a commercial formulation. SLU-PP-332 and SLU-PP-915 are distinct molecules and should not be treated as interchangeable.

Source index

Identity and product documentation

Confirm molecular identity, batch identification, analytical methods and the actual formulation before relating a commercial material to a publication. A purity percentage alone does not establish all of those facts.

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